Researchers have developed a vitamin B12–based therapy capable of crossing the blood-brain barrier to target glioblastoma tumors effectively. In animal studies, the compound preferentially accumulated in tumor tissue and delivered sustained nitric oxide directly to cancer cells. This approach enhanced the tumor-suppressing effects of current glioblastoma treatments, offering a potential new avenue for therapy against this aggressive brain cancer.
Vitamin B12-Based Compound Shows Promise in Targeting Glioblastoma

The Gist
“A novel vitamin B12–based compound crosses the blood-brain barrier to deliver nitric oxide to glioblastoma tumors, boosting the efficacy of existing treatments.”

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